The anticipated project utilizes a unique cohort comprising of high-quality cancer samples from different sites (tubo-ovarian, omentum, peritoneum, and ascites) and time points (primary diagnosis and recurrence) to gather proteogenomic data on cancer metastasis and disease recurrence. Exome sequencing combined with RNA sequencing and proteomics will allow to identify chemotherapy responders, mechanisms of disease recurrence and generate a comprehensive multi-omic data.