Platform for Proteomics
The lay summary for this project is work-in-progress.
Publications
Patents / Startups
Publications
- Choi M, Carver J, Chiva C, Tzouros M, Huang T, Tsai T-H, et al. quant: A community resource of quantitative mass spectrometry–based proteomics datasets. Nat Methods. 2020;17: 981–984. doi:10.1038/s41592-020-0955-0
- Čuklina J, Lee CH, Williams EG, Sajic T, Collins BC, Rodríguez Martínez M, et al. Diagnostics and correction of batch effects in large-scale proteomic studies: a tutorial. Mol Syst Biol. 2021;17: e10240. doi:10.15252/msb.202110240
- Forny P, Bonilla X, Lamparter D, Shao W, Plessl T, Frei C, et al. Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency. Nature Metabolism. 2023;5: 80–95. doi:10.1038/s42255-022-00720-8
- Fossati A, Li C, Uliana F, Wendt F, Frommelt F, Sykacek P, et al. PCprophet: a framework for protein complex prediction and differential analysis using proteomic data. Nat Methods. 2021;18: 520–527. doi:10.1038/s41592-021-01107-5
- Frey K, Goetze S, Rohrer L, von Eckardstein A, Wollscheid B. Decoding Functional High-Density Lipoprotein Particle Surfaceome Interactions. Int J Mol Sci. 2022;23. doi:10.3390/ijms23169506
- Frey K, Rohrer L, Potapenko A, Goetze S, von Eckardstein A, Wollscheid B. Mapping the dynamic cell surface interactome of high-density lipoprotein reveals Aminopeptidase N as modulator of its endothelial uptake. bioRxiv. 2023. p. 2023.01.03.522574. doi:10.1101/2023.01.03.522574
- Goetze S, Frey K, Rohrer L, Radosavljevic S, Krützfeldt J, Landmesser U, et al. Reproducible Determination of High-Density Lipoprotein Proteotypes. J Proteome Res. 2021;20: 4974–4984. doi:10.1021/acs.jproteome.1c00429
- Goetze S, Schüffler P, Athanasiou A, Koetemann A, Poyet C, Fankhauser CD, et al. Use of MS-GUIDE for identification of protein biomarkers for risk stratification of patients with prostate cancer. Clin Proteomics. 2022;19: 9. doi:10.1186/s12014-022-09349-x
- Lee S, Weiss T, Bühler M, Mena J, Lottenbach Z, Wegmann R, et al. Targeting tumour-intrinsic neural vulnerabilities of glioblastoma. bioRxiv. 2022. p. 2022.10.07.511321. doi:10.1101/2022.10.07.511321
- Nina ZilaOssia M. EichhoffIrene SteinerThomas MohrAndrea BileckPhil F. ChengAlexander LeitnerLudovic GilletTatjana SajicSandra GoetzeBetty FriedrichPatricia BortelJohanna StroblRené ReitermaierSabrina A. HoganJulia M. Martínez-GómezRamon StaegerFelix TuchmannSophie PetersGeorg StaryMario KuttkeAdelheid Elbe-BuergerChristoph HoellerRainer KunstfeldWolfgang WeningerBernd WollscheidReinhard DummerLars E. FrenchChristopher GernerRuedi AebersoldMitchell P. LevesqueVerena Paulitschke; Proteomic profiling of advanced melanoma patients to predict therapeutic response to anti-PD-1 therapy. Clin Cancer Res 2023; https://doi.org/10.1158/1078-0432.CCR-23-0562
- Uliana F, Vizovisek M, Acquasaliente L, Ciuffa R, Fossati A, Frommelt F, Goetze S, et al. Mapping specificity, cleavage entropy, allosteric changes and substrates in blood proteases by a high-throughput protease screen. Nat Commun. 2021;12(1), 1693. https://doi.org/10.1038/s41467-021-21754-8
- Wendt F, Milani ES, Wollscheid B. Elucidation of host-virus surfaceome interactions using spatial proteotyping. Adv Virus Res. 2021;109: 105–134. doi:10.1016/bs.aivir.2021.03.002
- Xuan Y, Bateman NW, Gallien S, Goetze S, Zhou Y, Navarro P, et al. Standardization and harmonization of distributed multi-center proteotype analysis supporting precision medicine studies. Nat Commun. 2020;11: 5248. doi:10.1038/s41467-020-18904-9
Patents / Startups
Platform
Dr. Sandra Götze
ETH Zurich
Consortium
Status
In Progress
- Platform, SMOC
Funded by
